Kenichi Shimada Selected Research

(4- (bis(4- chlorophenyl)methyl)- 1- piperazinyl)(5- methyl- 4- nitro- 1,2- oxazol- 3- yl)methanone

2/2012

Development of small-molecule probes that selectively kill cells induced to express mutant RAS.

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Kenichi Shimada Research Topics

Disease

11	Inflammation (Inflammations) 01/2021 - 01/2011
10	Infections 01/2019 - 05/2002
9	Atherosclerosis 06/2020 - 11/2008
8	Neoplasms (Cancer) 01/2021 - 09/2010
6	Vasculitis (Vasculitides) 10/2021 - 08/2012
5	Hypoxia (Hypoxemia) 01/2020 - 02/2014
4	Pneumonia (Pneumonitis) 02/2015 - 04/2009
3	Acute Lung Injury 01/2020 - 02/2014
3	Ventilator-Induced Lung Injury 01/2020 - 01/2015
3	Chlamydophila Infections 01/2019 - 11/2010
3	Mucocutaneous Lymph Node Syndrome (Kawasaki Disease) 01/2017 - 12/2015
2	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2020 - 02/2014
2	Hyperlipidemias (Hyperlipidemia) 01/2019 - 01/2018
2	Wounds and Injuries (Trauma) 01/2019 - 05/2002
2	Anemia 10/2018 - 01/2016
2	Seasonal Allergic Rhinitis (Hay Fever) 01/2018 - 02/2005
2	Syndactyly (Polysyndactyly) 04/2017 - 01/2016
2	Arteritis 02/2017 - 03/2012
2	Enophthalmos 06/2015 - 03/2014
2	Hyperplasia 03/2015 - 02/2015
2	Mitochondrial Diseases (Mitochondrial Disease) 03/2012 - 01/2011
1	Neuroblastoma 01/2020
1	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2020
1	Alopecia (Baldness) 01/2020
1	Bites and Stings (Sting) 01/2020
1	Autoimmune Diseases (Autoimmune Disease) 01/2020
1	Disease Progression 01/2020
1	COVID-19 01/2020
1	Neoplasm Metastasis (Metastasis) 04/2019
1	Breast Neoplasms (Breast Cancer) 04/2019
1	Cachexia 01/2019
1	IgA Vasculitis (Purpura, Schoenlein Henoch) 01/2019
1	Body Weight (Weight, Body) 01/2019
1	IGA Glomerulonephritis (IGA Nephropathy) 01/2019
1	MYD88 Deficiency 10/2018
1	Glioblastoma (Glioblastoma Multiforme) 01/2018

Drug/Important Bio-Agent (IBA)

14	InflammasomesIBA 10/2021 - 01/2011
8	CytokinesIBA 01/2018 - 11/2008
6	Proteins (Proteins, Gene)FDA Link 01/2021 - 03/2012
6	LipidsIBA 06/2020 - 11/2010
4	Pharmaceutical PreparationsIBA 01/2021 - 03/2015
4	Interleukin-1 (Interleukin 1)IBA 01/2017 - 02/2014
4	Interleukin-6 (Interleukin 6)IBA 02/2015 - 11/2008
3	InterleukinsIBA 01/2020 - 12/2015
3	Adenosine Triphosphate (ATP)IBA 01/2019 - 03/2012
3	Niacinamide (Nicotinamide)FDA LinkGeneric 01/2015 - 09/2012
3	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 02/2014 - 01/2011
3	ApolipoproteinsIBA 08/2012 - 11/2008
2	LDL Receptors (LDL Receptor)IBA 06/2020 - 08/2012
2	InterferonsIBA 01/2020 - 08/2012
2	LipopolysaccharidesIBA 01/2020 - 04/2015
2	XenobioticsIBA 01/2019 - 01/2018
2	Toll-Like Receptor 4IBA 10/2018 - 07/2009
2	Fondaparinux (Arixtra)FDA Link 10/2018 - 01/2016
2	edoxabanIBA 10/2018 - 01/2016
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2018 - 03/2014
2	Mitochondrial DNA (mtDNA)IBA 09/2016 - 03/2012
2	NucleotidesIBA 09/2016 - 02/2014
2	Leucine (L-Leucine)FDA Link 09/2016 - 02/2014
2	AntralIBA 06/2015 - 03/2014
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 03/2015 - 01/2015
2	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 03/2015 - 02/2014
2	Apolipoproteins E (ApoE)IBA 03/2015 - 11/2008
2	EnzymesIBA 01/2015 - 01/2012
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 08/2012 - 11/2008
2	Interleukin-12 Subunit p40IBA 11/2010 - 11/2008
2	Inosine Monophosphate (IMP)IBA 05/2009 - 01/2007
1	mitoquinoneIBA 01/2021
1	Testosterone (Sustanon)FDA Link 06/2020
1	Estrogens (Estrogen)FDA Link 06/2020
1	DNA (Deoxyribonucleic Acid)IBA 01/2020
1	Anti-Idiotypic AntibodiesIBA 01/2020
1	cyclic guanosine monophosphate-adenosine monophosphateIBA 01/2020
1	Small Molecule LibrariesIBA 01/2020
1	Immunoglobulin G (IgG)IBA 01/2020
1	AlbuminsIBA 01/2020
1	Interferon Type IIBA 01/2020
1	TrehaloseIBA 01/2020
1	pristane (pristan)IBA 01/2020
1	Polypropylenes (Polypropylene)IBA 04/2019
1	Dietary Fats (Dietary Fat)IBA 01/2019
1	Phosphotransferases (Kinase)IBA 01/2019
1	Secretory Immunoglobulin A (SIgA)IBA 01/2019
1	Immunoglobulin A (IgA)IBA 01/2019
1	Biomarkers (Surrogate Marker)IBA 01/2019
1	AnticoagulantsIBA 10/2018
1	Myeloid Differentiation Factor 88IBA 10/2018
1	CopperIBA 01/2018
1	MetalsIBA 01/2018
1	PurinesIBA 01/2018
1	NSC319726IBA 01/2018

Therapy/Procedure

3	Artificial Respiration (Mechanical Ventilation) 01/2020 - 02/2014
2	Skin Transplantation (Skin Grafting) 01/2019 - 04/2017
2	Therapeutics 01/2017 - 12/2015
2	Bone Transplantation (Bone Grafting) 06/2015 - 03/2014
1	Ovariectomy (Oophorectomy) 06/2020
1	Castration 06/2020
1	Mastectomy (Mammectomy) 04/2019
1	Myocutaneous Flap 04/2019
1	Hip Replacement Arthroplasty (Total Hip Replacement) 10/2018